What is Sulbutiamine? How Does it Help You?

Sulbutiamine is a synthetic derivative of thiamine or vitamin B1, which has many benefits when it comes to improvement of the brain’s cognitive functions. It is made from two vitamin B1 molecules that are joined together. This chemical bond of two vitamin B1 molecules helps Sulbutiamine to cross the blood-brain barrier easily and more efficiently than thiamine.

Sulbutamine has positive effects on memory, depression, fatigue, mood, and even erectile dysfunction. This is why the drug is used as a nootropic and is one of the most important components of the nootropic stack. Apart from having nootropic qualities, Sulbutiamine supplement also helps the physical body as well.

The thiamine present in the compound is a coenzyme used by the human body to metabolize food for producing energy. This also helps in maintaining heart health, nerve health, and improve brain functions. Also, thiamine helps in converting carbohydrates into glucose, which provides energy to the nervous system and the brain. Thiamine also helps in the development of myelin sheaths that protects the neurons from damage.

 Here are some things that Sulbutiamine helps you in:

Brain optimization – Sulbutiamine contains thiamine, which is critical for increasing energy, focus, and preventing memory loss. This can also keep the body away from inflammation and pain.

Mood enhancement – Thiamine present in Sulbutiamine is studied to enhance mood very effectively. The drug helps you combat various mental problems, like stress, anxiety, depression, and various other things. Thiamine also motivates you to some degree and also makes your brain stronger and capable of dealing with stress and anxiety.

Neurotransmitters – Sulbutiamine is essential for the production of the neurotransmitter called acetylcholine. Acetylcholine helps the neurons communicate efficiently and easily. It is also crucial for cognition, memory, and learning.

How does Sulbutiamine work in the brain?

Sulbutiamine helps the brain health in various ways. However, two benefits of the drug stand out among them:

  1. Sulbutiamine is a fat-soluble molecule which crosses the blood-brain barrier more efficiently than thiamine. Once you take the drug and it reaches the brain, it increases the levels of thiamine pyrophosphate (TPP) in the brain. TPP is directly involved in the citric acid cycle in the brain.
    This cycle helps in breaking the amino acids, fatty acids, and the monosaccharides into tiny molecules that produce adenosine triphosphate (ATP) energy for the mitochondria present in your cells. It also helps in producing molecules that help in building your body.
  2. Sulbutiamine helps the body to produce the enzyme PDH, which is important to make the neurotransmitter acetylcholine. The enzyme also helps in the synthesis of myelin, which creates a protective shield around the neurons and prevents them from damage. This makes sure that the communication among the neurons never stops.


Now that you know about the benefits and the uses of Sulbutiamine, you might want to take the Sulbutiamine supplements for your overall body development. If that’s the case, you need to know the doses that you need to take to make sure there are no side effects of the drug. The recommended dosage for Sulbutiamine is 400 mg to 1000 mg per day. If you’re planning to take higher doses, you can split with one dose in the morning and one in the evening.

Some reports suggest that you should not take the supplement late in the day since it can interfere with your sleep. This is why you might need to consult a doctor before starting to take the supplement on your own.